Hepatic Iron Overload following Liver Transplantation from a C282Y/H63D Compound Heterozygous Donor
نویسندگان
چکیده
منابع مشابه
Microcytic Anemia and Hepatic Iron Overload in a Child with Compound Heterozygous Mutations in Dmt1
Divalent metal transporter 1 (DMT1) mediates apical iron uptake in duodenal enterocytes and iron transfer from the transferrin receptor endosomal cycle into the cytosol in erythroid cells. Both mk mice and Belgrade rats, which carry an identical DMT1 mutation, exhibit severe microcytic anemia at birth, defective intestinal iron absorption and erythroid iron utilization. We report the hematologi...
متن کاملMicrocytic anemia and hepatic iron overload in a child with compound heterozygous mutations in DMT1 (SCL11A2).
Divalent metal transporter 1 (DMT1) mediates apical iron uptake in duodenal enterocytes and iron transfer from the transferrin receptor endosomal cycle into the cytosol in erythroid cells. Both mk mice and Belgrade rats, which carry an identical DMT1 mutation, exhibit severe microcytic anemia at birth and defective intestinal iron use and erythroid iron use. We report the hematologic phenotype ...
متن کاملLiving-Donor Liver Transplantation From a Heterozygous Parent for Infantile Refsum Disease.
Infantile Refsum disease (IRD) is a rare autosomal recessive disorder of peroxisome biogenesis characterized by generalized peroxisomal metabolic dysfunction, including accumulation of very long-chain fatty acids (VLCFAs) and phytanic acid (PA), as well as decreased plasmalogen contents (PL). An effective therapy for this intractable disease has not been established, and only supportive managem...
متن کاملA case of gastric cancer following living donor liver transplantation.
Only a few cases of de novo malignancy, especially gastric cancer after living donor liver transplantation (LDLT), have been reported. We report a case of gastric cancer following LDLT, after which immunosuppressants were minimized in accordance with the results of the mixed lymphocyte reaction (MLR) assay. A 65-year-old woman had previously undergone LDLT for hepatocellular carcinoma associate...
متن کاملHepatic iron overload in aceruloplasminaemia.
We report the case of a 52 year old male with diabetes mellitus and long standing evidence of hepatic iron excess. Initially considered to have haemochromatosis, this patient was reevaluated when hepatic iron stores were found to be unaffected by a prolonged course of weekly phlebotomy. The development of neurological disease prompted diagnostic consideration of aceruloplasminaemia, which we co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Case Reports in Hepatology
سال: 2018
ISSN: 2090-6587,2090-6595
DOI: 10.1155/2018/4298649